Huntington’s Disease Care Education and Research Center: Clinical Trials

Huntington’s Disease Clinical Trials

Active, Currently Enrolling:

  • Enroll-HD is a worldwide observational study for family members affected by Huntington’s disease, including spouses. Participants attend an annual study session at where they undergo a series of movement, behavioral and task-oriented tests, as well as a quality-of-life evaluation. Participants also may choose to donate a small volume of blood.​

Active, Not Enrolling:

  • SIGNAL-HD is designed to assess the safety, tolerability, and effectiveness of VX15, a novel monoclonal antibody in people with late prodromal or early manifest Huntington’s disease (HD). It is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study at 20 sites across the United States that seeks to enroll approximately 84 individuals, 21 or older, who are either early in the progression of the disease or are not yet diagnosed with the disease.