Georgetown University Neurology Clinical Research (GUNCR)

Actively Enrolling Trials

(Current as of November 7th, 2020)

Click on the diagnoses below to see our actively enrolling trials

Click on the name of a trial to view the trial’s page on clinicaltrials.gov

ALS, Myasthenia Gravis (MG), & Spinal Muscular Atrophy (SMA)

Observational study to examine safety, tolerability, and effectiveness of SPINRAZA® prescribed as part of standard of care (SAS Trial)
- Study Coordinator: Sarai Bartlett (ssb92@georgetown.edu)
ALS Postmortem Tissue Bank
- Coordinator: Galam Khan, MD (gak2@georgetown.edu)

Epilepsy

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. (CORE-VNS)
- Study Coordinator: Sandeep Pamula (sp1210@georgetown.edu)

Migraine and Headache Disorders

Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches (CP-2019-001)
- Study Coordinator: Chris Gough (ccg46@georgetown.edu)
Efficacy, Safety, and Tolerability of Atogepant for the Prevention of Chronic Migraine (PROGRESS 3101-303-002)
- Study Coordinator: Chris Gough (ccg46@georgetown.edu)

Multiple Sclerosis (MS)

A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (O’HAND)
- Study Coordinator: David Pisfil (ddp39@georgetown.edu)
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial (TREAT-MS)
- Study Coordinator: Derek Haase (drh57@georgetown.edu)
Feasibility of the Multiple Sclerosis Performance Test in Participants With Multiple Sclerosis (MSPT)
- Study Coordinator: Derek Haase (drh57@georgetown.edu)
A Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Patients With Multiple Sclerosis (OCARINA)
- Study Coordinator: Derek Haase (drh57@georgetown.edu)

Neuromyelitis Optica (NMO)

A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder (ECU-NMO-303)
- Study Coordinator: David Pisfil (ddp39@georgetown.edu)

Parkinson’s Disease (PD)

Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (SEQUOIA)
- Study Coordinator: Sandeep Pamula (sp1210@georgetown.edu)

Orally Administered ENT-01 for Parkinson’s Disease-Related Constipation (KARMET)
- Study Coordinator: Luke Lovelace (LL928@georgetown.edu)
Product Surveillance Registry (PSR)
- Study Coordinator: David Pisfil (ddp39@georgetown.edu)
PROSEEK: A Phase 2 Study In Early Parkinson’s Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706 (CLR_18_06)
- Study Coordinator: Luke Lovelace (LL928@georgetown.edu)
Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension (RESTORE)
- Study Coordinator: Sandeep Pamula (sp1210@georgetown.edu)

Stroke

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke (ARCADIA)
- Study Coordinator: Derek Haase (drh57@georgetown.edu)

Current Staff